Hugo Ten Cate Selected Research

Thrombin

6/2022	Relationships between coagulation factors and thrombin generation in a general population with arterial and venous disease background.
3/2021	Thrombin-Fibrin(ogen) Interactions, Host Defense and Risk of Thrombosis.
1/2021	Thrombin generation is associated with ischemic stroke at a young age.
1/2021	Activated factor XI-antithrombin complex presenting as an independent predictor of 30-days mortality in out-of-hospital cardiac arrest patients.
1/2021	Pleiotropic actions of factor Xa inhibition in cardiovascular prevention: mechanistic insights and implications for anti-thrombotic treatment.
1/2021	Suggestions for global coagulation assays for the assessment of COVID-19 associated hypercoagulability.
9/2020	Characterization of Thrombin Generation Curve Shape in Presence of Platelets from Acute Venous Thromboembolism Patients.
5/2020	Emergencies on direct oral anticoagulants: Management, outcomes, and laboratory effects of prothrombin complex concentrate.
1/2020	Thrombin generation in cardiovascular disease and mortality - results from the Gutenberg Health Study.
1/2020	Acute exacerbations of COPD are associated with a prothrombotic state through platelet-monocyte complexes, endothelial activation and increased thrombin generation.

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Hugo Ten Cate Research Topics

Disease

38	Thrombosis (Thrombus) 07/2022 - 12/2004
33	Hemorrhage 11/2022 - 09/2003
19	Venous Thrombosis (Deep-Vein Thrombosis) 06/2022 - 07/2010
12	Atrial Fibrillation 02/2022 - 01/2016
12	Venous Thromboembolism 01/2022 - 11/2016
12	Inflammation (Inflammations) 01/2022 - 02/2004
10	COVID-19 01/2022 - 08/2020
10	Neoplasms (Cancer) 11/2021 - 04/2011
9	Stroke (Strokes) 01/2022 - 12/2007
9	Thrombophilia 01/2022 - 12/2004
9	Cardiovascular Diseases (Cardiovascular Disease) 02/2021 - 02/2010
8	Disseminated Intravascular Coagulation 04/2021 - 09/2003
7	Thrombocytopenia (Thrombopenia) 01/2022 - 09/2003
7	Atherosclerosis 01/2021 - 12/2004
5	Vascular Diseases (Vascular Disease) 06/2022 - 03/2014
5	Ischemic Stroke 01/2022 - 03/2015
5	Pulmonary Embolism 07/2021 - 12/2014
5	Coronary Artery Disease (Coronary Atherosclerosis) 02/2021 - 08/2013
5	Peripheral Arterial Disease 01/2020 - 03/2015
5	Wounds and Injuries (Trauma) 01/2019 - 01/2013
4	Thromboembolism 12/2021 - 01/2012
4	Hemophilia A (Haemophilia) 12/2019 - 09/2008
4	Acute Coronary Syndrome 01/2019 - 02/2012
3	Embolism (Embolus) 01/2022 - 10/2016
3	Sepsis (Septicemia) 01/2022 - 01/2004
3	Obesity 02/2021 - 12/2019
3	Postthrombotic Syndrome 08/2020 - 07/2010
3	Atherosclerotic Plaque (Atheroma) 01/2019 - 12/2004
3	Fibrosis (Cirrhosis) 01/2017 - 08/2008
3	Polycythemia Vera 09/2011 - 11/2008
3	Essential Thrombocythemia 09/2011 - 11/2008
2	Antiphospholipid Syndrome (Antiphospholipid Antibody Syndrome) 12/2021 - 11/2020
2	Venous Insufficiency 10/2021 - 01/2018
2	Reperfusion Injury 08/2021 - 06/2016
2	Leukemia 04/2021 - 01/2018
2	Heart Failure 01/2021 - 07/2019
2	Infections 10/2020 - 01/2020
2	Lymphoma (Lymphomas) 01/2020 - 01/2018
2	Disease Susceptibility (Diathesis) 12/2019 - 03/2012
2	Hypertension (High Blood Pressure) 12/2019 - 01/2016
2	Multiple Trauma (Multiple Injuries) 11/2017 - 12/2015
2	Renal Insufficiency (Renal Failure) 01/2017 - 01/2005
2	Infarction (Infarctions) 06/2016 - 12/2007
2	Myocardial Infarction 03/2015 - 04/2010
2	Type 2 Diabetes Mellitus (MODY) 02/2010 - 02/2004

Drug/Important Bio-Agent (IBA)

32	Thrombin FDA Link 06/2022 - 09/2008
32	AnticoagulantsIBA 01/2022 - 02/2004
11	Blood Coagulation Factors (Coagulation Factor)IBA 06/2022 - 10/2011
11	Hemostatics (Antihemorrhagics)IBA 05/2022 - 12/2012
11	Biomarkers (Surrogate Marker)IBA 02/2022 - 06/2017
11	FibrinIBA 03/2021 - 01/2004
10	Fibrinogen (Factor I)FDA Link 05/2021 - 12/2004
10	Vitamin K FDA Link 12/2020 - 06/2010
8	fibrin fragment D (D-dimer)IBA 05/2021 - 12/2004
7	Heparin (Liquaemin)FDA LinkGeneric 12/2021 - 09/2003
6	Factor XIa (Coagulation Factor XIa)IBA 01/2022 - 01/2016
6	Dabigatran FDA Link 05/2020 - 12/2015
5	Biological ProductsIBA 08/2021 - 01/2010
5	Dacarbazine (DIC)FDA LinkGeneric 04/2021 - 09/2003
5	Prothrombin (Factor II)IBA 12/2020 - 12/2012
5	Thromboplastin (Tissue Factor)IBA 01/2020 - 12/2004
4	CollagenIBA 01/2022 - 03/2015
4	C-Reactive ProteinIBA 05/2021 - 12/2004
4	Factor Xa (Coagulation Factor Xa)IBA 01/2021 - 03/2014
4	idarucizumabIBA 05/2020 - 01/2017
4	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2019 - 03/2015
4	RivaroxabanIBA 01/2019 - 01/2018
3	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2017
3	EnzymesIBA 12/2021 - 01/2018
3	Interleukin-6 (Interleukin 6)IBA 12/2021 - 12/2004
3	4- ((1,4,8,11- tetraazacyclotetradec- 1- yl)methyl)benzoic acidIBA 05/2021 - 12/2014
3	Adenosine Diphosphate (ADP)IBA 05/2021 - 02/2012
3	estropipate (Ogen)FDA LinkGeneric 03/2021 - 03/2004
3	Peptide Hydrolases (Proteases)FDA Link 01/2021 - 01/2017
3	Factor Xa InhibitorsIBA 12/2020 - 07/2019
3	Clopidogrel (Plavix)FDA Link 01/2019 - 08/2011
3	ThrombomodulinIBA 03/2012 - 12/2004
2	CoagulantsIBA 06/2022 - 12/2019
2	Tissue Plasminogen Activator (Alteplase)FDA Link 08/2021 - 05/2021
2	Warfarin (Coumadin)FDA LinkGeneric 07/2021 - 07/2018
2	lipoprotein-associated coagulation inhibitor (TFPI)IBA 02/2021 - 01/2017
2	2'- deoxythymidylyl- (3'- 5')- 2'- deoxyadenosine (d(AT))IBA 01/2021 - 01/2018
2	Factor VIII (Coagulation Factor VIII)IBA 10/2020 - 09/2008
2	IntegrinsIBA 06/2019 - 03/2015
2	ApolipoproteinsIBA 01/2019 - 01/2008
2	Indicators and Reagents (Reagents)IBA 01/2018 - 09/2003
2	Glucose (Dextrose)FDA LinkGeneric 01/2016 - 02/2010
2	DNA (Deoxyribonucleic Acid)IBA 08/2013 - 01/2004
2	Protein CIBA 03/2012 - 11/2008
2	P-SelectinIBA 04/2011 - 12/2007

Therapy/Procedure

34	Therapeutics 06/2022 - 07/2010
6	Extracorporeal Membrane Oxygenation 11/2022 - 01/2020
5	Compression Stockings 01/2022 - 07/2010
5	Percutaneous Coronary Intervention 05/2021 - 04/2010
4	Catheters 07/2022 - 01/2020
4	Critical Care (Surgical Intensive Care) 08/2021 - 01/2020
4	Stents 01/2021 - 04/2010
3	Platelet Transfusion (Blood Platelet Transfusions) 01/2020 - 09/2003
2	Home Nursing (Nursing, Home) 11/2021 - 08/2020
2	Duration of Therapy 11/2018 - 01/2018